Small Protein, Big Impact: Microprotein Discovery Offers Hope for Obesity and Aging

on
Researchers have uncovered a tiny but powerful protein that helps keep our cells’ energy factories humming – a discovery that could spark new approaches to tackling obesity and age-related decline. Scientists at the Salk Institute in La Jolla found that a  “microprotein”  in mouse fat cells plays a critical role in maintaining healthy  mitochondria , the structures that generate energy in our cells. By preserving mitochondrial function, this diminutive protein helps cells burn fuel efficiently, which in turn could influence body weight and the aging process. The findings shine light on how molecular biology connects to everyday health, opening the door to  science-backed strategies for better metabolism and longevity. Mature brown fat cells from a mouse, with the newly discovered microprotein shown in red inside mitochondria (green) and nuclei in blue. This tiny protein helps preserve mitochondrial health under stress. (Credit: Salk Institute) Mighty Mitochondria in ...

Anxiety during pregnancy affects babies

on
A new study published in the journal Paediatric and Perinatal Epidemiology reveals that anxiety in pregnant women impacts their babies' size and gestational age. Specifically, women with more severe and chronic anxiety during pregnancy are more likely to have affected babies. Shahla M. Hosseini, Minhnoi W. Biglan, Cynthia Larkby, Maria M. Brooks, Michael B. Gorin, and Nancy L. Day studied a sample of low-income women, half of whom were African American and the other half Caucasian. The group already had well-known risk factors such as alcohol and cigarette use. The authors demonstrated that the mother's anxiety during pregnancy impacts birth outcomes over and beyond factors such as drug use, education, and race.

Anxiety during the third trimester predicted women delivering significantly smaller babies. In the first and second trimesters, the effects of anxiety were significant only among those women who had severe anxiety.

Low to moderate levels of anxiety in women during either the first or second trimester did not significantly affect the birth outcomes, but women who are severely anxious during much of their pregnancy should be considered for anxiety-reducing interventions.

"One way to prevent health problems in children and adults is to focus care on the prenatal period," the authors note. "It is key to pursue further research which addresses interventions to ameliorate the effects that a woman's trait anxiety has on the development of fetuses." Source: Wiley-Blackwell.

Comments

Post a Comment