Small Protein, Big Impact: Microprotein Discovery Offers Hope for Obesity and Aging

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Researchers have uncovered a tiny but powerful protein that helps keep our cells’ energy factories humming – a discovery that could spark new approaches to tackling obesity and age-related decline. Scientists at the Salk Institute in La Jolla found that a  “microprotein”  in mouse fat cells plays a critical role in maintaining healthy  mitochondria , the structures that generate energy in our cells. By preserving mitochondrial function, this diminutive protein helps cells burn fuel efficiently, which in turn could influence body weight and the aging process. The findings shine light on how molecular biology connects to everyday health, opening the door to  science-backed strategies for better metabolism and longevity. Mature brown fat cells from a mouse, with the newly discovered microprotein shown in red inside mitochondria (green) and nuclei in blue. This tiny protein helps preserve mitochondrial health under stress. (Credit: Salk Institute) Mighty Mitochondria in ...

Hitech hydroponics could bring urban agriculture

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Terry Fujimoto sees the future of agriculture in the exposed roots of the leafy greens he and his students grow in thin streams of water at a campus greenhouse. The program run by the California State Polytechnic University agriculture professor is part of a growing effort to use hydroponics -- a method of cultivating plants in water instead of soil -- to bring farming into cities, where consumers are concentrated.

Because hydroponic farming requires less water and less land than traditional field farming, Fujimoto and researchers-turned-growers in other U.S. cities see it as ideal to bring agriculture to apartment buildings, rooftops and vacant lots. "The goal here is to look at growing food crops in small spaces," he said. Long a niche technology existing in the shadow of conventional growing methods, hydroponics is getting a second look from university researchers and public health advocates. Supporters point to the environmental cost of trucking produce from farms to cities, the loss of wilderness for farmland to feed a growing world population, and the risk of bacteria along extensive, insecure food chains as reasons for establishing urban hydroponic farms.

However, the expense of setting up the high-tech farms on pricey city land and providing enough year-round heat and light could present some insurmountable obstacles. "These are university theories," said Jim Prevor, editor of Produce Business magazine. "They're not mapped to things that actually exist." The roots of hydroponically produced fruits and vegetables can dangle in direct contact with water or be set in growing media such as sponges or shredded coconut shells. Most commercial operations pump water through sophisticated sensors that automatically adjust nutrient and acidity levels in the water.

Hydroponics are generally used for fast-growing, high-value crops such as lettuces and tomatoes that can be produced year-round in heated, well-lit greenhouses. So far, production is not large enough for the U.S. Department of Agriculture to track.
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