Small Protein, Big Impact: Microprotein Discovery Offers Hope for Obesity and Aging

Researchers have uncovered a tiny but powerful protein that helps keep our cells’ energy factories humming – a discovery that could spark new approaches to tackling obesity and age-related decline. Scientists at the Salk Institute in La Jolla found that a  “microprotein”  in mouse fat cells plays a critical role in maintaining healthy  mitochondria , the structures that generate energy in our cells. By preserving mitochondrial function, this diminutive protein helps cells burn fuel efficiently, which in turn could influence body weight and the aging process. The findings shine light on how molecular biology connects to everyday health, opening the door to  science-backed strategies for better metabolism and longevity. Mature brown fat cells from a mouse, with the newly discovered microprotein shown in red inside mitochondria (green) and nuclei in blue. This tiny protein helps preserve mitochondrial health under stress. (Credit: Salk Institute) Mighty Mitochondria in ...

Rice grown in United States contains less-dangerous form of Arsenic

Rice grown in the United States may be safer than varieties from Asia and Europe, according to a new global study of the grain that feeds over half of humanity. The study evaluated levels of arsenic, which can be toxic at high levels, in rice worldwide. Yamily J. Zavala and colleagues point out that rice is a potentially important source of human exposure to arsenic, especially in populations with rice-based diets. Arsenic in rice is of special concern because it accumulates in much higher concentrations in rice than other staple grain crops. The researchers discovered that arsenic contamination of irrigation water was more important than soil contamination in increasing arsenic levels in rice.

Using global arsenic data, the researchers classified rice into two types, where the predominant arsenic forms were either organic or the more toxic inorganic forms. They found that rice from the United States largely contains organic arsenic, which is less easily absorbed into the body and excreted more rapidly than inorganic arsenic. Rice contaminated with inorganic arsenic prevails in Asia and Europe. The study suggests that breeding new rice varieties that convert inorganic arsenic to organic arsenic would be an "important risk reduction strategy, especially for countries like Bangladesh and India with arsenic contaminated environments and high rice consumption rates." via American Chemical Society.

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