Small Protein, Big Impact: Microprotein Discovery Offers Hope for Obesity and Aging

on
Researchers have uncovered a tiny but powerful protein that helps keep our cells’ energy factories humming – a discovery that could spark new approaches to tackling obesity and age-related decline. Scientists at the Salk Institute in La Jolla found that a  “microprotein”  in mouse fat cells plays a critical role in maintaining healthy  mitochondria , the structures that generate energy in our cells. By preserving mitochondrial function, this diminutive protein helps cells burn fuel efficiently, which in turn could influence body weight and the aging process. The findings shine light on how molecular biology connects to everyday health, opening the door to  science-backed strategies for better metabolism and longevity. Mature brown fat cells from a mouse, with the newly discovered microprotein shown in red inside mitochondria (green) and nuclei in blue. This tiny protein helps preserve mitochondrial health under stress. (Credit: Salk Institute) Mighty Mitochondria in ...

Once again grasshoppers inspired a new technology, a Jumping Microrobot

on
Researchers from the Laboratory of Intelligent Systems at EPFL are unveiled a novel, grasshopper-inspired jumping robot at the IEEE International Conference on Robotics and Automation May 21 in Pasadena, California. The robot weighs a miniscule 7 grams, and can jump 1.4 meters, or more than 27 times its body size -- ten times farther for its size and weight than any existing jumping robot. These jumpers could be fitted out with tiny sensors to explore rough, inaccessible terrain or to aid in search and rescue operations. "This biomimetic form of jumping is unique because it allows micro-robots to travel over many types of rough terrain where no other walking or wheeled robot could go," explains EPFL Professor Dario Floreano. "These tiny jumping robots could be fitted with solar cells to recharge between jumps and deployed in swarms for extended exploration of remote areas on Earth or on other planets." Small jumping animals such as fleas, locusts, grasshoppers and frogs use elastic storage mechanisms to slowly charge and quickly release their jumping energy. In this way, they can achieve very powerful jumps and very high accelerations.

The jumping robot presented here uses the exact same principle, charging two torsion springs via a small 0.6-gram pager motor and a cam. In order to be able to optimize the jumping performance, the legs can be adjusted for jumping force, takeoff angle and force profile during the acceleration phase. The tiny battery on board allows it to make up to 320 jumps at intervals of 3 seconds. This work was presented by Mirko Kovac on May 21 in Pasadena, California during the ICRA's "Dynamic Walking" Session. Kovac will also demonstrate the robot in the "robot zoo" at the 4th International Symposium on Adaptive Motion of Animals and Machines in Cleveland, OH on June 5, 2008. The LIS, directed by Professor Dario Floreano, focuses on the development of robotic systems and artificial intelligence methods inspired by biological principles of self-organization.

Comments

Post a Comment