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Showing posts from 2014

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Brain Ages Fast With Less Sleep

on July 02, 2014

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Elevated Activity in Hippocampus Linked to Alzheimer's

on July 01, 2014

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This Compound May Halt Progression of Alzheimer's

on June 28, 2014

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Stress in Early Life No Good For Brain

on June 28, 2014

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Bipolar Disorder Basic Biology

on February 13, 2014

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MitoQ Significantly Reverses Multiple Sclerosis-like Disease in Mice

on January 02, 2014

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Butterfly effect and autism spectrum disorder

A study conducted by researchers at the RIKEN Center for Brain Science (CBS) has shed light on the genetics of Autism Spectrum Disorder (ASD). They found that a particular type of genetic mutation contributes to ASD differently than typical mutations. By analyzing mutations in the genomes of individuals and their families, the researchers discovered that the three-dimensional structure of the genome can cause mutations to affect neighboring genes associated with ASD, even without mutations in ASD-related genes. The study was published in the scientific journal Cell Genomics on January 26. ASD is a group of conditions characterized by repetitive behaviors and social interaction difficulties. Although the condition runs in families, its heritability is complex and only partially understood. According to studies, the high heritability cannot be explained by merely looking at the part of the genome responsible for protein coding. Instead, the answer could lie in the non-coding regions of t...

Rethinking Cannabis: Unlocking the Genetic Blueprint of an Ancient Powerhouse

Cannabis has played a critical role in human societies for over ten millennia. Although contemporary attention often centers on its psychoactive component, THC (tetrahydrocannabinol), historically this plant served as an essential source of seed oil, textiles, and nourishment. Despite its longstanding significance, cannabis remains relatively underexplored and underexploited in modern agriculture. Recent legislative changes in the United States—most notably the 2014 and 2018 Farm Bills—have spurred renewed interest in cultivating cannabis for medicinal, grain, and fiber purposes. A team at the Salk Institute has now produced the most exhaustive and precise genetic atlas of cannabis to date. By examining 193 distinct cannabis genomes, researchers uncovered remarkable genetic diversity and complexity within this foundational crop. This collaborative effort involved Oregon CBD, Oregon State University, and the HudsonAlpha Institute for Biotechnology, and culminated in findings published i...

Understanding the Complex Interplay: Dementia and Genetic Changes

Introduction: Dementia is a challenging and multifaceted condition that affects millions of individuals worldwide. As our understanding of the factors contributing to dementia expands, one crucial aspect gaining attention is the role of genetic changes. This blog post aims to explore the intricate relationship between dementia and genetic factors, shedding light on the complexities of this neurological disorder. I. The Genetic Landscape of Dementia: Dementia encompasses a range of cognitive disorders, with Alzheimer's disease being the most prevalent form. While environmental factors and lifestyle choices play a role in dementia development, genetic changes are increasingly recognized as significant contributors. A. Familial Patterns: Research has identified certain familial patterns in dementia, indicating a genetic predisposition for some individuals. Families with a history of dementia may carry specific gene variants that increase the risk of developing the condition. Understan...

Autism and Eye Contact: Genes very much are involved

We have now a lot of evidence on genetic components in many disorders including neurological in both adults and kids. Autism is one such problem that has many genes involved. Research is still in full swing to find more genes and related pathways. However, one can find autistic features more phenotypically before genotyping. Eye contact is one of them. Studies have shown that autistic kids make less eye contact. This has been shown to have genetic component now. New research has uncovered compelling evidence that genetics plays a major role in how children look at the world and whether they have a preference for gazing at people's eyes and faces or at objects. The discovery by researchers at Washington University School of Medicine in St. Louis and Emory University School of Medicine in Atlanta adds new detail to understanding the causes of autism spectrum disorder. The results show that the moment-to-moment movements of children's eyes as they seek visual information about the...

Traumatic brain injury and dementia: A Missing link

Although much research has examined traumatic brain injury (TBI) as a possible risk factor for later life dementia from neurodegenerative diseases such as Alzheimer's disease (AD), little is known regarding how TBI influences the rate of age-related cognitive change. A new study now shows that history of TBI (with loss of consciousness) does not appear to affect the rate of cognitive change over time for participants with normal cognition or even those with AD dementia. More than 10 million individuals worldwide are affected annually by TBI, however the true prevalence is likely even greater given that a majority of TBIs are mild in severity and may not be recognized or reported. TBI is a major public health and socioeconomic concern resulting in $11.5 billion in direct medical costs and $64.8 billion in indirect costs to the U.S. health system in 2010 alone. According to the researchers the relationship between TBI and long-term cognitive trajectories remains poorly understood...

Unraveling the Mysteries: Exploring New Genetic Variants Related to Dementia

Introduction: Dementia, a debilitating condition affecting millions worldwide, has long been a subject of intense research. Scientists and researchers have tirelessly worked towards understanding its underlying causes, and recent breakthroughs in genetics have brought forth new hope. This blog post delves into the latest discoveries surrounding genetic variants linked to dementia, shedding light on the potential implications for both diagnosis and treatment. The Human Genome Project and Beyond: Advancements in genetic research, particularly since the completion of the Human Genome Project, have paved the way for a deeper understanding of the intricate relationship between genes and various health conditions, including dementia. The identification of specific genetic variants associated with an increased risk of developing dementia has become a pivotal focus. Key Genetic Variants: Recent studies have unveiled several genetic variants implicated in the onset and progression of dementia. ...

Food allergy risk in infants linked to avocado consumption in pregnant women

Journal: Pediatric Research. 10.1038/s41390-025-03968-4 An observational study among 2,272 mother-child pairs in Finland found that infants had 44% lower odds of developing food allergies at 12 months if their mother consumed fresh avocado during pregnancy, after adjusting for other lifestyle, delivery, and maternal health factors. Decades of research have explored the relationship between maternal diet and allergic outcomes in infants, but this is the first published study to link avocados in the maternal diet to a lower risk of infant food allergies—a growing public health concern that affects nearly one in 13 children, or roughly two in every classroom, according to Food Allergy Research and Education(FARE). Given food allergy has reached epidemic levels, the Avocado Nutrition Center supported this research to grow the world’s understanding of how avocado, a food with nutrients that support fetal and infant development, may further benefit children....

Boy With 5 Chambered Heart

The doctors of the cardiological center in the Kemerovo region were shocked when they made ultrasonic examination and saw the heart of a newborn baby Vanya Maryin. He was born with a 5-chamber heart. Only bees have such heart constitution. Funny enough the ‘bee-boy’, as doctors called him, comes from the beekeeper’s family. The family remembers a wonderful inherited bee yard that Vanya’s grandfather held, and his wife that ran the ‘bee-business’ after his death. Her bees produced the best honey in the district. Vanya was born not with 2 atriums like all the people on the Earth, but with an additional - third one. He could die anytime from a sudden push, fright or even happiness. But the body, adjusting to an unusual 5-chamber ‘bee-heart’, suggested the boy a saving, optimal ‘pose for life’. Another interesting read related to this story ‘The boy’s heart had 5 chambers instead of 4. Usually the heart consists of the right atrium and the right ventricle, the left atrium and the left ...

Another study on "Do Cell Phones Increase Brain Cancer Risk"

Major research initiatives are needed immediately to assess the possibility that using cellular phones may lead to an increased risk of brain tumors, according to an editorial in the November issue of the journal Surgical Neurology. Recent studies have raised concerns that long-term exposure to electromagnetic fields (ELF) from cell-phone handsets can increase the risk of brain cancers and other nervous system tumors, according to the editorial by Dr. Ron Pawl, a neurosurgeon at Lake Forest Hospital, Lake Forest, Ill. He calls for collaborative research initiatives to determine whether the link between cell phones and brain cancer is real. Scientists have long been concerned over the possibility that ELF exposure may increase the risk of brain cancers. Until recently, however, research has shown no clear link between cell phone use and brain tumors. Earlier this year, a Swedish research group published an epidemiologic study suggesting an increased risk of brain cancers (gliomas) as we...

Navigating the Landscape of Dementia: Unveiling the Current Risk Factors in 2024

Dementia, a condition characterized by a decline in cognitive abilities affecting daily life, has become a growing concern worldwide. As we step into 2024, it's crucial to explore the latest insights into dementia and its associated risk factors. Understanding these factors is essential for early detection, prevention, and providing better care for those affected. Age: Age remains one of the primary risk factors for dementia. As individuals grow older, the likelihood of developing dementia increases. While it's not an inevitable consequence of aging, the risk does rise significantly after the age of 65. Researchers continue to study the complex interplay of genetic and environmental factors contributing to age-related cognitive decline. Genetics: Genetic factors play a pivotal role in dementia risk. Advances in genomic research have identified certain genes associated with an increased susceptibility to dementia. Familial history can be a crucial indicator, with some individual...

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