Small Protein, Big Impact: Microprotein Discovery Offers Hope for Obesity and Aging

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Researchers have uncovered a tiny but powerful protein that helps keep our cells’ energy factories humming – a discovery that could spark new approaches to tackling obesity and age-related decline. Scientists at the Salk Institute in La Jolla found that a  “microprotein”  in mouse fat cells plays a critical role in maintaining healthy  mitochondria , the structures that generate energy in our cells. By preserving mitochondrial function, this diminutive protein helps cells burn fuel efficiently, which in turn could influence body weight and the aging process. The findings shine light on how molecular biology connects to everyday health, opening the door to  science-backed strategies for better metabolism and longevity. Mature brown fat cells from a mouse, with the newly discovered microprotein shown in red inside mitochondria (green) and nuclei in blue. This tiny protein helps preserve mitochondrial health under stress. (Credit: Salk Institute) Mighty Mitochondria in ...

First Kevlar fabrics that can kill a wide range of infectious agents including virus and bacteria

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Protective clothing worn by firemen and other emergency workers may soon get a germ-fighting upgrade. Researchers in South Dakota report progress toward the first Kevlar fabrics that can kill a wide range of infectious agents, including bacteria, viruses, and the spores that cause anthrax. In the new study, Yuyu Sun and Jie Luo point out that Kevlar fabrics are widely used as fire-resistant materials for firefighters, police and emergency medical workers. But amid increased threats of bioterrorism, there's a growing need for new protective clothing that can also provide multiple protection against a wide variety of dangerous microorganisms.

Photo: A coated Kevlar fabric exposed to a fungus called Candida tropicalis.(Credit: Courtesy of the American Chemical Society)The scientists developed a special process to coat Kevlar samples with acyclic N-Halamine, a potent germ-fighting substance. They then exposed coated and uncoated fabric samples to E. coli, Staphylococcus aureus, Candida tropicalis (a fungus), MS2 virus, and Bacillus subtilis spores (to mimic anthrax). After a short time, large amounts of microorganisms stuck to untreated fabric samples, but the coated fabrics showed little to no adherence of the infectious agents, the researchers say. The coating is long-lasting, can be reactivated, and does not cause any loss of fabric comfort or strength, they add. Source: Amer. Chem. Society.

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