Small Protein, Big Impact: Microprotein Discovery Offers Hope for Obesity and Aging

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Researchers have uncovered a tiny but powerful protein that helps keep our cells’ energy factories humming – a discovery that could spark new approaches to tackling obesity and age-related decline. Scientists at the Salk Institute in La Jolla found that a  “microprotein”  in mouse fat cells plays a critical role in maintaining healthy  mitochondria , the structures that generate energy in our cells. By preserving mitochondrial function, this diminutive protein helps cells burn fuel efficiently, which in turn could influence body weight and the aging process. The findings shine light on how molecular biology connects to everyday health, opening the door to  science-backed strategies for better metabolism and longevity. Mature brown fat cells from a mouse, with the newly discovered microprotein shown in red inside mitochondria (green) and nuclei in blue. This tiny protein helps preserve mitochondrial health under stress. (Credit: Salk Institute) Mighty Mitochondria in ...

Red and White wine shown to be good for heart

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Sciencedaily reports a new study, scheduled for the Aug. 23 issue of the ACS Journal of Agricultural & Food Chemistry, challenges the idea that red wine is more heart-healthy white wine. Past studies indicated that the cardioprotective compounds in grapes -- polyphenolic antioxidants -- reside in the skin and seeds. Grape skins, which contain purple pigment, are crushed with the pulp to make red wines. But the skins are separated from the pulp to make most white wine. That situation led to the conventional belief that red wines and red grape juice are the most heart healthy.

Dipak K. Das, of the University Of Connecticut School Of Medicine, headed the study. It was done with colleagues form the University of Milan and several other research institutes in Italy. "Although further study is needed to identify the principle ingredients responsible for the cardioprotective abilities of the grape flesh, to the best of our knowledge, our study provides evidence for the first time that the flesh of grapes is equally cardioprotective with respect to the skins," the researchers report.

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